SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3325dcea052fa7e9dfd2f66d614ee454c504006342b0a2b019b2f8bd854c88e' 
  AND token = 'F/S6X003SbrqOQBisDgFTL3Bic700C6GlggbsDt06g4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}