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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22be3e99297c20be0c75f26d5960acd9366051f38a27ad4d6ddc4097f4c5efc0' 
  AND token = 'fZHrugRvGsVHcvGNRrCilOYs3fCzr3s0QegG0hFr/Ck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}