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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '754b8b27111cddb01a0fecd3bec90711ff850d559ce22ffdf29f568b40181622' 
  AND token = 'eVNS2dwTcrYJob3YIl5WfN71Cg/1lYZzgBEiXqQ6q8o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}