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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f45442ef06fadc1158759e27d3b667774e6a7e06b881e5b5f174ec5dd052b16a' 
  AND token = 'IIZ7P4qTAB08JNYylK2ySq1eAwWjMuT8xR2V19KWjgE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}