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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a75a2734d76d3f80972e5aa0c37a44983d64d287556cd340ecb101c8739e411c' 
  AND token = 'bvDpB254AKTLAxkbDMFIOeeiraAS3wqBs7Q7prUFwyA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}