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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68aebbb8bb38036df0c063930b61aa85249519d0b88da6ca3b8a8e69a0dfaab8' 
  AND token = 'xoWKmT7l4y5UVVl1mSfaDC0PFYUzSiWEkMXcmeeFrzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}