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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9db422239cb5dc31888090cb1f34af64b1ff510ca4f40a39bf87d57069423e12' 
  AND token = 'tbNl6F8FnbRZF6ZLmnmBHLaysfiCeDVWQZfGGp0/6Ac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}