SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57392f06970ace8906ea99630e646190b74cc929c3e57e3fde9fc87896f9b2cc' 
  AND token = 'ee6MbDFNdUgh4tox7lzFy28DbL2cg8JaTMK+jOPwzX0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}