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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b7c4abfc66bea0013f5f26e64eab44f58a3487bb9ba4926dd79422b2ae8d061' 
  AND token = 'nMDnZ1CpFH6ODk/MffMEeQD7mM3YHR9CxO1o1YjDR+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}