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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54fb8480bffaf41e3918ee59f7920bce6ee8f90d21db7f90f28339826151c548' 
  AND token = 'wIosHe3aYVbWOqUfvVX/IVDfW4CwhegmlDmGfBXfAqU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}