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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '465a69d5f7d3f4c28e8817b0eea8e35b3c3e6d4088c12087904b1786314b529a' 
  AND token = 'ZAaSZswSHYL/OhWf066Ux7hdLLcRwWq4msa0GCuB9Ao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}