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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17d28b1bcec22b0789f10e3db73e6fe2642ac37357bfefa7859616ff12990cdc' 
  AND token = 'Cpe7S78Ul+neptsOoHIxA49t15AjcI/83ZuIb2+Nom4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}