SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd81dd808e5de4beeb0612aa811a68f76bba4fd00c99f535a8231eb5974979f9d' 
  AND token = 'JyApIr0RShSpEJN4ysoSAoE5FFKH4186UcXRwDKE0/s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}