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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e38e1f19ebffb65b32683f09c65a9caa79a6e69212c080d330adcddc8607f97b' 
  AND token = 'AEqCL46+kE7bECdwVoZ++sWQMJFg4N5NLszt9RL/9Xg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}