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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e21d91b41feabe57bda102cc071c76f88a7e4dead0db947cd8e1fb716843e73' 
  AND token = 'vfZ6yCSTEeP775VMUs65XqalIZb5NaePBxVIY7Uv2pQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}