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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48fbe4ab5b925e178c42b77658a3bf22ffdcbcdafaabebfd0b1cef32a5ef86d2' 
  AND token = 'Pi2VpIVTRV1F7qHLNTP6KWvVwMJAqKphHfrpAG56wmY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}