SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d07277f41ca6d04f38f23cd2891cdde120f7be1aa43e258b79a4ecb1505c31a' 
  AND token = 'MVKkf0Agz6rVO8M7NM7K2YgTMBmwHMTXL/jPygwls8k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}