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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b100b70eefae31b243ee836fa50200faa3b93ed665d256695fc124ea2bb3441' 
  AND token = '46qWDY1ZRS9Q3S9IAUejJXtdkOuWO3HD/PjtKm0qeE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}