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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f182603eca46a30b9be30d95cc92c1baed609a7c30a617d49d8646da0d3c798' 
  AND token = '+1a7V823oAaUC6Yu5Jiu2XkANIRUPKXN+du0jo/D9+Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}