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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c5c643b9a44a82dabbde6107156eebef50e031d61339e2a2be2999c2cf5a926' 
  AND token = 'vXuN/7x46MSs0V3eY8LvHfBX58IFWfhuJ7QklCS5puo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}