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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ea458f3d2c216e98b78ed6b66ab768b06536e954fbb5952cae63f647bea5ea3' 
  AND token = 'D+qEyCr/+12p/5UMG0dErZssWbdg4tGfrkPRLOHw9oM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}