SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d05d228c18eb944c6530e278bc6036fbb4603a77bcd94ddb48f4743a4697ed6' 
  AND token = 'L5qdeNK4dLpFMxp+doDcP34lxklYV+loCwiqy3KgD24=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}