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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '735165b2df8612d47720748407444b407196c4e8ac3814b3c15f9318b24f8bb1' 
  AND token = 'w+DhBbmEREakfFr3dI09eigiI0qd05xiBtpxq2pX2eI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}