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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19d5a79a42717ec37cf3848aa49b1ab491fde9f2e36ff1b24028332e7b968572' 
  AND token = '43o1uuDygPKgQTVtjeR7FVcymuf2W5ZVHfsSJMCA2Eo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}