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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8f00f934ac6d81dff9cb5a27dcc0a067bdb5d0e50ddb4c2d7f12009dc9c532d' 
  AND token = 'qFDGva0JyJdzZd1WgNGJNx81wLFiLXirn5Wl9WCV7T0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}