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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a07e33f534b6dd170e5064b070066f8e5ef4b530cf05652b8b477b4971b99127' 
  AND token = '+sdR7pyGUbY6zq5d4Mp1D+ErbJ0NMI/AlrbZ159P3IU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}