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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05770e4b77b77982d7f6e5dd77896c04cdf3fbe5247f6d42db7cab296eadde2b' 
  AND token = 'zPXupmWeKE8Rt+qNOCzNZbOvoakRcu0Gas/D2qzHzDo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}