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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0761e42faefc7cb5b10e3b26154cf121134928aeceb28f76936399d17508bfd3' 
  AND token = '9kRvUeZ9UEcK28q9V1vuKNi4hkgFbBa21FiyZ6imDiw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}