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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7256cce9760ae2f7d5f8333e980681c90e3357f0601903063bb304ce4e757b5' 
  AND token = 'u0XHLUzFtkBZdWOdJHXLTBXPXSKkLKEqIXgfY6pW9Do=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}