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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '553f48b99084feb8693ab3c0e45c4fca82334a2010dcea5fab79ddf44c9908bf' 
  AND token = 'PYWBBRF+cIYRdKGp42oKwO8+4RBJwkPQ2SpvyDNVKTg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}