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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efce63ac4a6b56dbfa03da906ce55339034b3a3ecd1d766f693e28fcc6f37650' 
  AND token = 'Ulmp39t+1LIgUO7HZG68UZ07wVYglxaWmSMr26eQRnQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}