SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06d58dc5bd49432cea585f7b15d01836088c97f8d1592882070b77f78e6ef4c7' 
  AND token = '5/1cNswDVRwRNIyDsUwVBtNW4IN05qzhip2Lx+Fd7Qs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}