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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42217799b7f08028e22065fe9fecd62a17668379c12069c26f89010304bd07c0' 
  AND token = 'EqJdyMCZlMYRtF3fu4jIaeZKnuV9PJi8vkRp/sQACmk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}