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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c5a3da96140efb77e3d66f3a6f755034f0201ede4a8eb8e57587155525f9f0a' 
  AND token = '0fgWkHr7do2tQe7qgqqxWj1hx7oCk6hDYUoBo/nd/Ro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}