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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45424fdd635e0eab71a03f596dd7e828591e56bb55e70b70b48691c32f75f6de' 
  AND token = 'W2HTXtc7yDQlSIBIfCoq1fr4lCf1YnaKQgCt6jboCMA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}