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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '562148e5f190ef6fd808a966b84d618e3ec2f57eeb3206cfa99c31f99933644b' 
  AND token = 'xRMm9Lyxu11IULmwSnnMyKLtffWJBNWUMyRAsa7xC7c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}