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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e4c0a6300f3296b9a44696a6e30b8656d79a1bd63f78883c3f1475f33f40b74' 
  AND token = '0E2Pa06BiiHhKS/5wDVYWifUN7xUDp5VMwxXTcyRZvg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}