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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b41c388ebe710217dd52ec3e91e8b24a4bc8834a1dec497678a70048b560497a' 
  AND token = 'k2niRNRD12n8oTI2nD24Uyi2lqxQ8LHC+14Aj/9hLjM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}