SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f934cde790e74a13bf334fd73f4dd3f66f6e2bc29e4a614bd50c6020c88b8b46' 
  AND token = 'EkzhjEqJ2aEvyYsTHShYsmvdDN96wxnCT/fOkfcYQno=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}