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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '059708685f97e4ee872c1ccba156fe4d18f32b229a580ad41bb4761c9a08be8f' 
  AND token = 'o6Gj5KCiHVS8Tzc3gSCjVdAU8zLnNYfu7CM03+xNXAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}