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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89125ab817bd680aa4fe4129b7e8e222a01d3b0a57894c0f894b3ae27fb88489' 
  AND token = 'H2sM2nXxjFigfWPJxVAG5vW9IAvHgPaUtLmBECAkvPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}