SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '757fc2254e970a77128e9968e68f79fdbe2578aedd245d1f5d76b56d8941dbfc' 
  AND token = 'MEiPjVwAOQb91wJcUFu9ia/9iywsGLWlE+pDk4gpYuA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}