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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0dbf340a2feebab8623a559aa3035b5d1019c4f1d05dc1423856a82491d864a' 
  AND token = 'Sz7zDqBWAqSLtt9rWVEFelLourpkFrwqZv/Ea7mSJFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}