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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52b9789e425df6b68e69cb9639baa2f88b83adf5a67aee80afa16623f969ef45' 
  AND token = 'YOoIyFB9BT3C3Z1quzfT30oVsyiFjmGbHZrXs2aL0jE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}