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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a12d75b06416cc5caca30d7cee51e9c78e927940d6e9be153b32b8f08626946a' 
  AND token = 'wpdYcGzaaAb9T4A8jHFSnQvVhR8KRcFCkFX+gbp+3yE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}