SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd00fba4b9bae9478b432cbe1f47180d3064e76bd98b92b768da7bdff6444e246' 
  AND token = 'VMMdPQi7grg93VSFpDN1D/YnyCCBkP9StkNEod+c57Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}