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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49500ef1c39d0f6e83113df91735b221b8a0e64f8b5c083cad7057174e543259' 
  AND token = 'QeykQF1LuT4oKXJLBwBDXunFlmODN2sP1DpKjkDYKIU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}