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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36b05608b1519c66ec340f86c7ffe858183d31950da762284018db59fa87f1cd' 
  AND token = 'WrSqloeGv6fSPxgil1/Bed9XwPV2VBbTM0e0aT5P8iY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}