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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fcd47938d4c1951e86aae2ffa43bf6ff74e6ddd3a4bc9f88f835dcf4f34f1499' 
  AND token = '8QoHYYGxfWwYN9TtoW6q60PtIsanzK9ZeSUmBf/agxk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}