SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae023ef13146424d96e870ff51264e427bb236693b8fa74fdb7b8acbcee5e2f8' 
  AND token = 'yCP7wHW3XvaonnOqDUv6PKFrFLy6lFCU5ASDd/SwRzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}